碧云天生物技术-Forskolin (腺苷酸环化酶激活剂)(S1612-25mg)

试剂> 抑制剂激活剂等> PKC、钙离子及脂信号通路> PKC Signaling

Forskolin (腺苷酸环化酶激活剂)

一键复制产品信息

产品编号: S1612-25mg

产品包装:25mg

选择包装

5mg/ml×0.2ml 5mg 25mg

数

量

说明书下载

价格: ¥ 1539.00

加入购物车

				产品简介
			
				使用说明
			
				产品文件
			
				相关产品
			
				相关论文
			
				产品问答

产品编号	产品名称	产品包装	产品价格
S1612-1mg	Forskolin (腺苷酸环化酶激活剂)	5mg/ml×0.2ml	179.00元
S1612-5mg	Forskolin (腺苷酸环化酶激活剂)	5mg	410.00元
S1612-25mg	Forskolin (腺苷酸环化酶激活剂)	25mg	1539.00元

Forskolin是一种常用的腺苷酸环化酶激活剂。Forskolin可以通透细胞，激活腺苷酸环化酶(adenylyl cyclase)，从而升高细胞内的cAMP水平。
Forskolin分子量为410.50，分子式为C₂₂H₃₄O₇，CAS Number：66575-29-9。本产品纯度大于99%。
本Forskolin为进口分装，其中5mg/ml包装产品用DMSO配制，共0.2ml。5mg和25mg包装为粉末装。
包装清单：

产品编号	产品名称	包装
S1612-1mg	Forskolin (腺苷酸环化酶激活剂)	5mg/ml×0.2ml
S1612-5mg	Forskolin (腺苷酸环化酶激活剂)	5mg
S1612-25mg	Forskolin (腺苷酸环化酶激活剂)	25mg
—	说明书	1份

保存条件：
-20℃避光保存。
注意事项：
本产品对人体有害，操作时请小心，并注意有效防护以避免直接接触人体或吸入体内。
本Forskolin在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内，可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。

使用说明：
1. Forskolin常见使用浓度范围为1-100μM。具体的最佳工作浓度请参考相关文献，或根据实验目的，以及所培养的特定细胞和组织，通过实验进行摸索和优化。

物质安全数据单

输入右侧验证码点击下载：

下载

质检证书

输入批号搜寻COA

搜索

相关产品请点击如下按钮：

PKC Signaling

使用本产品的文献：

1. Liang Wang, Chunling Wu, Wanling Peng, Ziliang Zhou, Jianzhi Zeng, Xuelin Li, Yini Yang, Shuguang Yu, Ye Zou, Mian Huang, Chang Liu, Yefei Chen, Yi Li, Panpan Ti, Wenfeng Liu, Yufeng Gao, Wei Zheng, Haining Zhong, Shangbang Gao, Zhonghua Lu, Pei-Gen Ren, Ho Leung Ng, Jie He, Shoudeng Chen, Min Xu, Yulong Li, Jun Chu

A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging

Nat Commun. 2022 Sep 12;13(1):5363. doi: 10.1038/s41467-022-32994-7. (IF 12.121)

2. Shen C, Li X, Rasooly A, Guo L, Zhang K, Yang M.

A single electrochemical biosensor for detecting the activity and inhibition of both protein kinase andalkaline phosphatase based on phosphate ions induced deposition of redox precipitates.

Biosens Bioelectron. 2016 Nov 15;85:220-5. (IF 10.257)

3. Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP.

Gq activity-andβ-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for malefertility.

Elife. 2018 Feb 2;7. pii: e33432. (IF 7.08)

4. Zhao X, Wei S, Li Z, Lin C, Zhu Z, Sun D, Bai R, Qian J, Gao X, Chen G, Xu Z

Autophagic flux blockage in alveolar epithelial cells is essential in silica nanoparticle-induced pulmonary fibrosis.

Cell Death Dis. 2019 Feb 12 10(2):127. (IF 6.304)

5. Sun F, Yang XJ, Lv HY, Tang YB, An SM, Ding XP, Li WB, Teng L, Shen Y, Chen HZ, Zhu L.

β2-Adrenoreceptor-Mediated Proliferation Inhibition of Embryonic Pluripotent Stem Cells.

J Cell Physiol. 2015 Nov;230(11):2640-6. (IF 5.546)

6. Chen G, Fu S, Feng W, Huang B, Xu S, Wang W, Liu J.

AMP010014A09 in Sus Scrofa Encodes an Analog of G Protein-Coupled Receptor 109A,Which Mediates the Anti-Inflammatory Effects of Beta-Hydroxybutyric Acid.

CELL PHYSIOL BIOCHEM. 2017;42(4):1420-1430. (IF 5.5)

7. Zhang Y, Chen ML, Zhou Y, Yi L, Gao YX, Ran L, Chen SH, Zhang T, Zhou X, Zou D, Wu B, Wu Y, Chang H, Zhu JD, Zhang QY, Mi MT.

Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway.

Mol Nutr Food Res. 2015 Aug;59(8):1443-57. (IF 5.309)

8. Lv P, Wang Y, Ma J, Wang Z, Li JL, Hong CS, Zhuang Z, Zeng YX.

Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair.

ONCOTARGET. 2014 Sep 15;5(17):7512-24. (IF 5.168)

9. Li Y, He J, Sui S, Hu X, Zhao Y, Li N.

Clenbuterol upregulates histone demethylase JHDM2a via the β(2)-adrenoceptor/cAMP/PKA/p-CREB signaling pathway.

Cell Signal. 2012 Dec;24(12):2297-306. (IF 3.968)

10. Mu X, He K, Sun H, Zhou X, Chang L, Li X, Chu W, Qiao G, Lu Y.

Hydrogen peroxide induces overexpression of angiotensin-converting enzyme in human veinendothelial cells.

FREE RADICAL RES. 2013 Feb;47(2):116-22. (IF 2.839)

11. Peng Y, Shi J, Du X, Wang L, Klocker H, Mo L, Mo Z, Zhang J.

Prostaglandin E2 induces stromal cell-derived factor-1 expression in prostate stromal cells by activating proteinkinase A and transcription factor Sp1.

INT J BIOCHEM CELL B. 2013 Mar;45(3):521-30. (IF 3.673)

12. Du B, Luo W, Li R, Tan B, Han H, Lu X, Li D, Qian M, Zhang D, Zhao Y, Liu M.

Lgr4/Gpr48 Negatively Regulates TLR2/4-associated Pattern Recognition and Innate Immunity by Targeting CD14Expression.

J Biol Chem. 2013 May 24;288(21):15131-41. (IF 4.238)

13. Liu F, You X, Wang Y, Liu Q, Liu Y, Zhang S, Chen L, Zhang X, Ye L.

The oncoprotein HBXIP enhances angiogenesis and growth of breast cancer through modulating FGF8 and VEGF.

Carcinogenesis. 2014 May;35(5):1144-53. (IF 4.603)

14. Zheng YF, Liu CF, Lai WF, Xiang Q, Li ZF, Wang H, Lin N.

The laxative effect of emodin is attributable to increased aquaporin 3 expression in the colon of mice and HT-29 cells.

Fitoterapia. 2014 Jul;96:25-32. (IF 2.527)

15. Hu QX, Dong JH, Du HB, Zhang DL, Ren HZ, Ma ML, Cai Y, Zhao TC, Yin XL, Yu X, Xue T, Xu ZG, Sun JP.

Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein.

J Biol Chem. 2014 Aug 29;289(35):24215-25. (IF 4.238)

16. Sun F, Ding XP, An SM, Tang YB, Yang XJ, Teng L, Zhang C, Shen Y, Chen HZ, Zhu L.

Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling.

SCI REP-UK. 2015 Oct 30;5:15950. (IF 3.998)

17. Yu ZL, Li DQ, Huang XY, Xing X, Yu RQ, Li Z, Li ZB.

Lysophosphatidic acid upregulates connective tissue growth factor expression in osteoblasts through theGPCR/PKC and PKA pathways.

Int J Mol Med. 2016 Feb;37(2):468-74. (IF 3.098)

18. Chen B, Lin T, Yang X, Li Y, Xie D, Cui H.

Intermittent parathyroid hormone (1-34) application regulates cAMP-response element binding proteinactivity to promote the proliferation and osteogenic differentiation of bone mesenchymal stromal cells, via the cAMP/PKA signaling pathway.

Exp Ther Med. 2016 Jun;11(6):2399-2406. (IF 1.785)

19. Jia B, Gao Y, Li M, Shi J, Peng Y, Du X, Klocker H, Sampson N, Shen Y, Liu M, Zhang J.

GPR30 Promotes Prostate Stromal Cell Activation via Suppression of ERα Expression and Its DownstreamSignaling Pathway.

Endocrinology. 2016 Aug;157(8):3023-35. (IF 3.934)

20. Chen T, Xu DZ, Li Q, Mou P, Zeng Z, Brass LF, Zhu L.

The regulation of Sema4D exodomain shedding by protein kinase A in platelets.

Platelets. 2016 Nov;27(7):673-679. (IF 3.378)

21. Shen XF, Teng Y, Sha KH, Wang XY, Yang XL, Guo XJ, Ren LB, Wang XY, Li J, Huang N.

Dietary flavonoid luteolin attenuates uropathogenic Escherichia. Coli invasion of the urinary bladder.

Biofactors. 2016 Nov 12;42(6):674-685. (IF 4.734)

22. Deng X, Deng L, Wang P, Cheng C, Xu K.

Post translational modification of CREB 1 decreases collagen I expression by inhibiting the TGF β1signaling pathway in rat hepatic stellate cells.

Mol Med Rep. 2016 Dec;14(6):5751-5759. (IF 2.1)

23. Xu Y, Zhao Y, Xu Y, Guan Y, Zhang X, Chen Y, Wu Q, Zhu G, Chen Y, Sun F, Wang J, Yu Y.

Blocking inhibition to YAP by ActinomycinD enhances anti-tumor efficacy of Corosolic acid in treating livercancer.

Cell Signal. 2017 Jan;29:209-217. (IF 3.968)

24. Xu Y, Zhao Y, Xu Y, Guan Y, Zhang X, Chen Y, Wu Q, Zhu G, Chen Y, Sun F, Wang J, Yu Y.

Blocking inhibition to YAP by ActinomycinD enhances anti-tumor efficacy of Corosolic acid in treating liver cancer.

Cell Signal. 2017 Jan;29:209-217. (IF 3.968)

25. Qian W, Gang X, Zhang T, Wei L, Yang X, Li Z, Yang Y, Song L, Wang P, Peng J, Cheng D, Xia Q.

Protein kinase A-mediated phosphorylation of the Broad-Complex transcription factor in silkworm suppresses its transcriptional activity.

J Biol Chem. 2017 Jul 28;292(30):12460-12470. (IF 4.238)

26. Wu Q, Wang Y, Qian M, Qiao Y, Zou S, Chen C, Zhang X, Chen Y, Zhao Y, Zhu G, Chen Y, Sun F, Wang J, Pan Q.

Sirt1 suppresses Wnt/βCatenin signaling in liver cancer cells by targeting βCatenin in a PKAα-dependent manner.

Cell Signal. 2017 Sep;37:62-73. (IF 3.968)

27. Zhou D, Kuang Z, Zeng X, Wang K, Ma J, Luo H, Chen M, Li Y, Zeng J, Li S, Luan F, He Y, Dai H, Liu B, Li H, He L, Xing Q.

p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to inducehyperpigmentation.

J Cell Mol Med. 2017 Oct;21(10):2465-2480. (IF 4.486)

28. Wang B, Chen T, Wang J, Jia Y, Ren H, Wu F, Hu M, Chen Y.

Methamphetamine modulates the production of interleukin-6 and tumor necrosis factor-alpha via the cAMP/PKA/CREB signaling pathway in lipopolysaccharide-activated microglia.

Int Immunopharmacol. 2018 Mar;56:168-178. (IF 3.943)

29. Zhang K, Zeng K, Shen C, Tian S, Yang M

Determination of protein kinase A activity and inhibition by using hydroxyapatite nanoparticles as a fluorescent probe.

Mikrochim Acta. 2018 Mar 16;185(4):225.

30. Ding Y, Cui J, Wang Q, Shen S, Xu T, Tang H, Han M, Wu X

The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice.

Obesity (Silver Spring). 2018 Aug;26(8):1303-1311.

31. Xiao Li, Shoupeng Wang, Xiaoli Yang, Hongjun Chu

miR‑142‑3p targets AC9 to regulate sciatic nerve injury‑induced neuropathic pain by regulating the cAMP/AMPK signalling pathway

Int J Mol Med. 2021 Feb;47(2):561-572. doi: 10.3892/ijmm.2020.4824. (IF 3.098)

32. Han Zhao, Lingyan Feng, Wei Zhong, Hongyan Zhen, Qingjia Chi, Xiang Wang

Hyperphosphorylation of Tau Due to the Interference of Protein Phosphatase Methylesterase-1 Overexpression by MiR-125b-5p in Melatonin Receptor Knockout Mice

Int J Mol Sci. 2021 Oct 31;22(21):11850. doi: 10.3390/ijms222111850. (IF 4.556)

33. Erling Hu, Qi Zhang, Sen Shang, Yinan Jiang, Xiaoyun Lu

Continuous wave irradiation at 0.1 terahertz facilitates transmembrane transport of small molecules

iScience. 2022 Feb 22;25(3):103966. doi: 10.1016/j.isci.2022.103966.

34. Wenfeng Liu, Chang Liu, Pei-Gen Ren, Jun Chu, Liang Wang

An Improved Genetically Encoded Fluorescent cAMP Indicator for Sensitive cAMP Imaging and Fast Drug Screening

Front Pharmacol. 2022 May 12:13:902290. doi: 10.3389/fphar.2022.902290. (IF 4.225)

35. Jing Wang, Bingyan Jiang, Kezhen Wang, Jianfeng Dai, Chunsheng Dong, Yipeng Wang, Peng Zhang, Min Li, Wei Xu, Lin Wei

A cathelicidin antimicrobial peptide from Hydrophis cyanocinctus inhibits Zika virus infection by downregulating expression of a viral entry factor

J Biol Chem. 2022 Oct;298(10):102471. doi: 10.1016/j.jbc.2022.102471. (IF 4.238)

浏览此产品的顾客也同时浏览：

S1612-1mg

5mg/ml×0.2ml

Forskolin (腺苷酸环化酶激活剂)

S1612-5mg

5mg

Forskolin (腺苷酸环化酶激活剂)

L-抗坏血酸(维生素C) (≥99.0%, Reagent grade)

S1672-250nmol

5mM×0.05ml

Ionomycin (钙离子载体)

用户名：
密码：
校验码：
	后续自动登录

	找回密码注册

新冠相关产品

试剂

核酸相关

多肽与蛋白

细胞相关

信号转导

抗体

抑制剂激活剂等

常用试剂

耗材

仪器

技术服务